Anti-TRPV4 Polyclonal Antibody (HC206014)

Name: Anti-TRPV4 Polyclonal Antibody
Brand: abinScience
SKU: HC206014
Price: 168 USD
Availability: InStock

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Precio(USD): --

Especificación:

50ug
100ug

Número:

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Datasheet
SDS

Vista general

Número de catálogo

HC206014

Descripción

Anti-TRPV4 Polyclonal Antibody (HC206014) is a rabbit polyclonal antibody detecting TRPV4. Suitable for Human, Rat, and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant TRPV4 (Arg151-Asn361).

Objetivo

OTRPC4, Osm-9-like TRP channel 4, TRP12, TRPV4, Transient receptor potential cation channel subfamily V member 4, Transient receptor potential protein 12, TrpV4, VR-OAC, VRL-2, VRL2, VROAC, Vanilloid receptor-like channel 2, Vanilloid receptor-like protein 2, Vanilloid receptor-related osmotically-activated channel

Nivel de endotoxinas

Please contact with the lab for this information.

Peso molecular observado

100 kDa

Purificación

Purified by antigen affinity column.

Número de acceso

Q9HBA0

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Envío

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Transient receptor potential cation channel subfamily V member 4 (TRPV4) is a ~98 kDa protein. Non-selective calcium permeant cation channel involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by heat, low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism.

1. Arniges, M. et al. (2006) The Journal of biological chemistry 281, 1580-6. PMID: 16293632

2. Köttgen, M. et al. (2008) The Journal of cell biology 182, 437-47. PMID: 18695040

3. Garcia-Elias, A. et al. (2008) The Journal of biological chemistry 283, 31284-8. PMID: 18826956

4. Fiorillo, C. et al. (2012) Neurogenetics 13, 195-203. PMID: 22526352

5. Thorneloe, KS. et al. (2012) Science translational medicine 4, 159ra148. PMID: 23136043

6. Doñate-Macián, P. et al. (2018) Nature communications 9, 2307. PMID: 29899501

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-TRPV4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-TRPV4 Polyclonal Antibody (HC206014)

Vista general

Imágenes

Referencias

Datasheet

SDS