Anti-TRPV4 Polyclonal Antibody (HC206014)

Name: Anti-TRPV4 Polyclonal Antibody
Brand: abinScience
SKU: HC206014
Price: 168 USD
Availability: InStock

Даташит Поделиться продуктом Копировать информацию

Цена(USD): --

Спецификация:

50ug
100ug

Количество:

Свяжитесь с нами

Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HC206014

Описание

Anti-TRPV4 Polyclonal Antibody (HC206014) is a rabbit polyclonal antibody detecting TRPV4. Suitable for Human, Rat, and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant TRPV4 (Arg151-Asn361).

Цель

OTRPC4, Osm-9-like TRP channel 4, TRP12, TRPV4, Transient receptor potential cation channel subfamily V member 4, Transient receptor potential protein 12, TrpV4, VR-OAC, VRL-2, VRL2, VROAC, Vanilloid receptor-like channel 2, Vanilloid receptor-like protein 2, Vanilloid receptor-related osmotically-activated channel

Уровень эндотоксинов

Please contact with the lab for this information.

Наблюдаемая молекулярная масса

100 kDa

Очистка

Purified by antigen affinity column.

Номер доступа

Q9HBA0

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Реконституция

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Доставка

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Transient receptor potential cation channel subfamily V member 4 (TRPV4) is a ~98 kDa protein. Non-selective calcium permeant cation channel involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by heat, low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism.

1. Arniges, M. et al. (2006) The Journal of biological chemistry 281, 1580-6. PMID: 16293632

2. Köttgen, M. et al. (2008) The Journal of cell biology 182, 437-47. PMID: 18695040

3. Garcia-Elias, A. et al. (2008) The Journal of biological chemistry 283, 31284-8. PMID: 18826956

4. Fiorillo, C. et al. (2012) Neurogenetics 13, 195-203. PMID: 22526352

5. Thorneloe, KS. et al. (2012) Science translational medicine 4, 159ra148. PMID: 23136043

6. Doñate-Macián, P. et al. (2018) Nature communications 9, 2307. PMID: 29899501

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-TRPV4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-TRPV4 Polyclonal Antibody (HC206014)

Обзор

Изображения

Ссылки

Даташит

SDS