

| Número de catálogo | HV012014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-TRPV5 Polyclonal Antibody (HV012014) is a rabbit polyclonal antibody detecting TRPV5 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human TRPV5 (Met1-Pro327). | ||||||||
| Objetivo | ECaC1, Calcium transport protein 2, Epithelial calcium channel 1, TRPV5, Osm-9-like TRP channel 3, ECAC1, Transient receptor potential cation channel subfamily V member 5, OTRPC3, CaT2, ECaC, TrpV5 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9NQA5 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Transient receptor potential cation channel subfamily V member 5 (TRPV5) is a ~82 kDa protein. Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. 1. Peng, JB. et al. (2001) Genomics 76, 99-109. PMID: 11549322 2. Zhang, W. et al. (2008) American journal of physiology. Renal physiology 295, F1472-84. PMID: 18768590 | ||||||||
| Nota | For research use only. |

Western blot analysis was performed using anti-TRPV5 polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate
Lane 2: 293T cell lysate
Lane 3: Saos2 cell lysate
Lane 4: HL-60 cell lysate
Lane 5: Siha cell lysate
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