

| Numéro de catalogue | HV012014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-TRPV5 Polyclonal Antibody (HV012014) is a rabbit polyclonal antibody detecting TRPV5 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human TRPV5 (Met1-Pro327). | ||||||||
| Cible | ECaC1, Calcium transport protein 2, Epithelial calcium channel 1, TRPV5, Osm-9-like TRP channel 3, ECAC1, Transient receptor potential cation channel subfamily V member 5, OTRPC3, CaT2, ECaC, TrpV5 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9NQA5 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Transient receptor potential cation channel subfamily V member 5 (TRPV5) is a ~82 kDa protein. Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. 1. Peng, JB. et al. (2001) Genomics 76, 99-109. PMID: 11549322 2. Zhang, W. et al. (2008) American journal of physiology. Renal physiology 295, F1472-84. PMID: 18768590 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-TRPV5 polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate
Lane 2: 293T cell lysate
Lane 3: Saos2 cell lysate
Lane 4: HL-60 cell lysate
Lane 5: Siha cell lysate
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