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| カタログ番号 | HY155014 | ||||||
|---|---|---|---|---|---|---|---|
| 説明 |
Anti-TXN Polyclonal Antibody (HY155014) is a rabbit polyclonal antibody detecting TXN in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||
| アプリケーション | ELISA, IHC, WB | ||||||
| 宿主種 | Rabbit | ||||||
| クローン性 | Polyclonal | ||||||
| アイソタイプ | IgG | ||||||
| 免疫原 | E. coli - derived recombinant Human TXN (Val2-Val105). | ||||||
| ターゲット | Trx, TXN, TRX1, SASP, Hom s Trx, Thioredoxin, ATL-derived factor, ADF, TRX, Surface-associated sulphydryl protein, TRDX | ||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||
| 精製 | Purified by antigen affinity column. | ||||||
| アクセッション番号 | P10599 | ||||||
| 形態 | Liquid | ||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||
| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| 背景 | Thioredoxin (TXN) is a ~11 kDa protein. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. 1. Limacher, A. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 178, 389-96. PMID: 17182577 2. Glaser, AG. et al. (2008) Allergy 63, 1617-23. PMID: 19032234 3. Jacquot, JP. et al. (1990) Biochemical and biophysical research communications 173, 1375-81. PMID: 2176490 4. Mitchell, DA. et al. (2005) Nature chemical biology 1, 154-8. PMID: 16408020 5. Mitchell, DA. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 11609-14. PMID: 17606900 6. Wei, SJ. et al. (2000) Cancer research 60, 6688-95. PMID: 11118054 7. Hirota, K. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 3633-8. PMID: 9108029 | ||||||
| 注意事項 | For research use only. |
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