

| Каталожный номер | HY155014 | ||||||
|---|---|---|---|---|---|---|---|
| Описание |
Anti-TXN Polyclonal Antibody (HY155014) is a rabbit polyclonal antibody detecting TXN in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||
| Применения | ELISA, IHC, WB | ||||||
| Хозяинский вид | Rabbit | ||||||
| Клоональность | Polyclonal | ||||||
| Изотип | IgG | ||||||
| Иммуноген | E. coli - derived recombinant Human TXN (Val2-Val105). | ||||||
| Цель | Trx, TXN, TRX1, SASP, Hom s Trx, Thioredoxin, ATL-derived factor, ADF, TRX, Surface-associated sulphydryl protein, TRDX | ||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||
| Очистка | Purified by antigen affinity column. | ||||||
| Номер доступа | P10599 | ||||||
| Форма | Liquid | ||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||
| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| Фон | Thioredoxin (TXN) is a ~11 kDa protein. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. 1. Limacher, A. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 178, 389-96. PMID: 17182577 2. Glaser, AG. et al. (2008) Allergy 63, 1617-23. PMID: 19032234 3. Jacquot, JP. et al. (1990) Biochemical and biophysical research communications 173, 1375-81. PMID: 2176490 4. Mitchell, DA. et al. (2005) Nature chemical biology 1, 154-8. PMID: 16408020 5. Mitchell, DA. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 11609-14. PMID: 17606900 6. Wei, SJ. et al. (2000) Cancer research 60, 6688-95. PMID: 11118054 7. Hirota, K. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 3633-8. PMID: 9108029 | ||||||
| Примечание | For research use only. |
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