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| カタログ番号 | HC057014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-UBAP2L Polyclonal Antibody (HC057014) is a rabbit polyclonal antibody detecting Ubiquitin-associated protein 2-like; Protein NICE-4; RNA polymerase II degradation factor UBAP2L; UBAP2L; KIAA0144; NICE4 in ELISA, IHC, WB. Suitable for Mouse and Human.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human UBAP2L (Gln30-Trp96). | ||||||||
| ターゲット | Ubiquitin-associated protein 2-like; Protein NICE-4; RNA polymerase II degradation factor UBAP2L; UBAP2L; KIAA0144; NICE4 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q80X50, Q14157 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ubiquitin-associated protein 2-like (UBAP2L) is a ~116 kDa protein. Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled nucleotide excision repair (TC-NER) machinery fails to resolve DNA damage. Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT-HSCs). Is a regulator of stress granule assembly, required for their efficient formation. Required for proper brain development and neocortex lamination. 1. Bordeleau, ME. et al. (2014) Blood 124, 2362-9. PMID: 25185265 2. Jia, X. et al. (2022) Science advances 8, eabo7112. PMID: 35977029 | ||||||||
| 注意事項 | For research use only |
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