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| カタログ番号 | HB411014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-UBXN2B Polyclonal Antibody (HB411014) is a rabbit polyclonal antibody detecting UBX domain-containing protein 2B; NSFL1 cofactor p37; p97 cofactor p37; UBXN2B in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human UBXN2B (Leu244-Lys331). | ||||||||
| ターゲット | UBX domain-containing protein 2B; NSFL1 cofactor p37; p97 cofactor p37; UBXN2B | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q14CS0, P0C627, Q0KL01 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | UBX domain-containing protein 2B (UBXN2B) is a ~37 kDa protein. Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. 1. Uchiyama, K. et al. (2006) Developmental cell 11, 803-16. PMID: 17141156 2. Kress, E. et al. (2013) The Journal of cell biology 201, 559-75. PMID: 23649807 | ||||||||
| 注意事項 | For research use only |
Lane 1: A549 cell lysate
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