

| Каталожный номер | HB411014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-UBXN2B Polyclonal Antibody (HB411014) is a rabbit polyclonal antibody detecting UBX domain-containing protein 2B; NSFL1 cofactor p37; p97 cofactor p37; UBXN2B in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant human UBXN2B (Leu244-Lys331). | ||||||||
| Цель | UBX domain-containing protein 2B; NSFL1 cofactor p37; p97 cofactor p37; UBXN2B | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q14CS0, P0C627, Q0KL01 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | UBX domain-containing protein 2B (UBXN2B) is a ~37 kDa protein. Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. 1. Uchiyama, K. et al. (2006) Developmental cell 11, 803-16. PMID: 17141156 2. Kress, E. et al. (2013) The Journal of cell biology 201, 559-75. PMID: 23649807 | ||||||||
| Примечание | For research use only |

Lane 1: A549 cell lysate
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