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| カタログ番号 | HB333014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-UFM1 Polyclonal Antibody (HB333014) is a rabbit polyclonal antibody detecting Ubiquitin-fold modifier 1; UFM1; C13orf20; BM-002 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Rat, and Zebrafish.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human UFM1 (Ser2-Gly83). | ||||||||
| ターゲット | Ubiquitin-fold modifier 1; UFM1; C13orf20; BM-002 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P61960, P61961, Q2KJG2, Q5BJP3, Q803Y4, Q5ZMK7, Q5RJW4, B5LVL2, P34661, A8DYH2, Q9CA23 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ubiquitin-fold modifier 1 (UFM1) is a ~9 kDa protein. Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1. Ufmylation is involved in various processes, such as ribosome recycling, response to DNA damage, transcription or reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress. 1. Komatsu, M. et al. (2004) The EMBO journal 23, 1977-86. PMID: 15071506 2. Tatsumi, K. et al. (2010) The Journal of biological chemistry 285, 5417-27. PMID: 20018847 3. Oweis, W. et al. (2016) Cell reports 16, 3113-3120. PMID: 27653677 4. Nahorski, MS. et al. (2018) Brain : a journal of neurology 141, 1934-1945. PMID: 29868776 5. Walczak, CP. et al. (2019) Proceedings of the National Academy of Sciences of the United States of America 116, 1299-1308. PMID: 30626644 6. He, C. et al. (2024) Molecular cell 84, 1120-1138.e8. PMID: 38377992 7. DaRosa, PA. et al. (2024) Nature 627, 445-452. PMID: 38383785 8. Yoo, HM. et al. (2014) Molecular cell 56, 261-274. PMID: 25219498 9. Liang, JR. et al. (2020) Cell 180, 1160-1177.e20. PMID: 32160526 | ||||||||
| 注意事項 | For research use only |
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