Anti-UFM1 Polyclonal Antibody (HB333014)

Name: Anti-UFM1 Polyclonal Antibody
Brand: abinScience
SKU: HB333014
Price: 168 USD
Availability: InStock

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Обзор

Каталожный номер

HB333014

Описание

Anti-UFM1 Polyclonal Antibody (HB333014) is a rabbit polyclonal antibody detecting Ubiquitin-fold modifier 1; UFM1; C13orf20; BM-002 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Rat, and Zebrafish.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human UFM1 (Ser2-Gly83).

Цель

Ubiquitin-fold modifier 1; UFM1; C13orf20; BM-002

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

P61960, P61961, Q2KJG2, Q5BJP3, Q803Y4, Q5ZMK7, Q5RJW4, B5LVL2, P34661, A8DYH2, Q9CA23

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Ubiquitin-fold modifier 1 (UFM1) is a ~9 kDa protein. Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1. Ufmylation is involved in various processes, such as ribosome recycling, response to DNA damage, transcription or reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

1. Komatsu, M. et al. (2004) The EMBO journal 23, 1977-86. PMID: 15071506

2. Tatsumi, K. et al. (2010) The Journal of biological chemistry 285, 5417-27. PMID: 20018847

3. Oweis, W. et al. (2016) Cell reports 16, 3113-3120. PMID: 27653677

4. Nahorski, MS. et al. (2018) Brain : a journal of neurology 141, 1934-1945. PMID: 29868776

5. Walczak, CP. et al. (2019) Proceedings of the National Academy of Sciences of the United States of America 116, 1299-1308. PMID: 30626644

6. He, C. et al. (2024) Molecular cell 84, 1120-1138.e8. PMID: 38377992

7. DaRosa, PA. et al. (2024) Nature 627, 445-452. PMID: 38383785

8. Yoo, HM. et al. (2014) Molecular cell 56, 261-274. PMID: 25219498

9. Liang, JR. et al. (2020) Cell 180, 1160-1177.e20. PMID: 32160526

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-UFM1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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