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| カタログ番号 | HY032014 | ||||||||
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| 説明 |
Anti-UMOD Polyclonal Antibody (HY032014) is a rabbit polyclonal antibody detecting UMOD in ELISA, IHC, WB. Suitable for Human, Dog, Bovine, and Pongo abelii.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human UMOD (Glu334-Ser589). | ||||||||
| ターゲット | Tamm-Horsfall urinary glycoprotein, THP, Uromodulin, UMOD | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P07911 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Uromodulin (UMOD) is a ~69 kDa protein. Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability (Probable). May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia. 1. Hession, C. et al. (1987) Science (New York, N.Y.) 237, 1479-84. PMID: 3498215 2. Schmid, M. et al. (2010) Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 26, 311-8. PMID: 20798515 | ||||||||
| 注意事項 | For research use only. |
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