

| カタログ番号 | HV482014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-UPB1 Polyclonal Antibody (HV482014) is a rabbit polyclonal antibody detecting UPB1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Pongo abelii.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human UPB1 (Trp121-Glu384). | ||||||||
| ターゲット | UPB1, N-carbamoyl-beta-alanine amidohydrolase, Beta-ureidopropionase, Beta-alanine synthase, BUP1, BUP-1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9UBR1 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Beta-ureidopropionase (UPB1) is a ~43 kDa protein. Catalyzes a late step in pyrimidine degradation. Converts N-carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N-carbamoyl-beta-aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide (Probable). 1. van Kuilenburg, AB. et al. (2012) Biochimica et biophysica acta 1822, 1096-108. PMID: 22525402 2. Nakajima, Y. et al. (2014) Journal of inherited metabolic disease 37, 801-12. PMID: 24526388 3. Van Kuilenburg, AB. et al. (1999) Analytical biochemistry 272, 250-3. PMID: 10415095 4. Vreken, P. et al. (1999) Biochimica et biophysica acta 1447, 251-7. PMID: 10542323 5. Sakamoto, T. et al. (2001) Journal of nutritional science and vitaminology 47, 132-8. PMID: 11508704 6. Maurer, D. et al. (2018) The Biochemical journal 475, 2395-2416. PMID: 29976570 | ||||||||
| 注意事項 | For research use only. |

Western blot analysis was performed using anti-UPB1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse liver lysate
Lane 2: Rat kidney lysate
Lane 3: Rat liver lysate


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