中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HB559014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-USP48 Polyclonal Antibody (HB559014) is a rabbit polyclonal antibody detecting Ubiquitin carboxyl-terminal hydrolase 48; 3.4.19.12; Deubiquitinating enzyme 48; Ubiquitin thioesterase 48; Ubiquitin-specific peptidase 48; Ubiquitin-specific protease 48; Ubiquitin-specific-processing protease 48; USP48; USP31 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Chicken.
Highlights
|
||||||||
| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human USP48 (Thr97-Thr422). | ||||||||
| ターゲット | Ubiquitin carboxyl-terminal hydrolase 48; 3.4.19.12; Deubiquitinating enzyme 48; Ubiquitin thioesterase 48; Ubiquitin-specific peptidase 48; Ubiquitin-specific protease 48; Ubiquitin-specific-processing protease 48; USP48; USP31 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q86UV5, Q3V0C5, Q76LT8, Q5ZM45 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ubiquitin carboxyl-terminal hydrolase 48 (USP48) is a ~119 kDa protein. Deubiquitinase that recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of polyubiquitin precursors as well as that of ubiquitinated proteins. Plays a role in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites. Plays an important role in cell cycle progression by deubiquitinating Aurora B/AURKB and thereby extending its stability. 1. Tzimas, C. et al. (2006) Cellular signalling 18, 83-92. PMID: 16214042 2. Bassani, S. et al. (2021) Human molecular genetics 30, 1785-1796. PMID: 34059922 3. Antao, AM. et al. (2021) International journal of molecular sciences 22. PMID: 34445214 4. Jantaree, P. et al. (2022) Cellular and molecular life sciences : CMLS 79, 461. PMID: 35913642 5. Sánchez-Bellver, L. et al. (2022) International journal of molecular sciences 23. PMID: 36293380 6. Ren, Y. et al. (2023) Cancer research 83, 1074-1093. PMID: 36607699 | ||||||||
| 注意事項 | For research use only |
お問い合わせ
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
