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Anti-UXT Polyclonal Antibody (HV545014)

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Vista general
Número de catálogoHV545014
Descripción
Anti-UXT Polyclonal Antibody (HV545014) is a rabbit polyclonal antibody detecting UXT in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human UXT (Glu15-His157).
Objetivo ART-27, Protein UXT, Ubiquitously expressed transcript protein, Androgen receptor trapped clone 27 protein, UXT
Purificación Purified by antigen affinity column.
Número de acceso Q9UBK9
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Protein UXT is a ~18 kDa protein. Involved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor AR-mediated transcription. Together with URI1, associates with chromatin to the NKX3-1 promoter region. Negatively regulates the transcriptional activity of the estrogen receptor ESR1 by inducing its translocation into the cytoplasm. May act as nuclear chaperone that facilitates the formation of the NF-kappa-B enhanceosome and thus positively regulates NF-kappa-B transcription activity.

1. Mita, P. et al. (2011) Molecular and cellular biology 31, 3639-52. PMID: 21730289
2. Sánchez-Morgan, N. et al. (2017) Journal of cellular biochemistry 118, 2347-2356. PMID: 28106301
3. Markus, SM. et al. (2002) Molecular biology of the cell 13, 670-82. PMID: 11854421
4. Sun, S. et al. (2007) The Journal of cell biology 178, 231-44. PMID: 17620405
5. Huang, Y. et al. (2011) Molecular biology of the cell 22, 1389-97. PMID: 21307340
6. Moss, TN. et al. (2007) In vitro cellular & developmental biology. Animal 43, 139-46. PMID: 17554592
Nota For research use only.
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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