

| Numéro de catalogue | HV545014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-UXT Polyclonal Antibody (HV545014) is a rabbit polyclonal antibody detecting UXT in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human UXT (Glu15-His157). | ||||||||
| Cible | ART-27, Protein UXT, Ubiquitously expressed transcript protein, Androgen receptor trapped clone 27 protein, UXT | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9UBK9 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Protein UXT is a ~18 kDa protein. Involved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor AR-mediated transcription. Together with URI1, associates with chromatin to the NKX3-1 promoter region. Negatively regulates the transcriptional activity of the estrogen receptor ESR1 by inducing its translocation into the cytoplasm. May act as nuclear chaperone that facilitates the formation of the NF-kappa-B enhanceosome and thus positively regulates NF-kappa-B transcription activity. 1. Mita, P. et al. (2011) Molecular and cellular biology 31, 3639-52. PMID: 21730289 2. Sánchez-Morgan, N. et al. (2017) Journal of cellular biochemistry 118, 2347-2356. PMID: 28106301 3. Markus, SM. et al. (2002) Molecular biology of the cell 13, 670-82. PMID: 11854421 4. Sun, S. et al. (2007) The Journal of cell biology 178, 231-44. PMID: 17620405 5. Huang, Y. et al. (2011) Molecular biology of the cell 22, 1389-97. PMID: 21307340 6. Moss, TN. et al. (2007) In vitro cellular & developmental biology. Animal 43, 139-46. PMID: 17554592 | ||||||||
| Note | For research use only. |
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