

| Каталожный номер | HV545014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-UXT Polyclonal Antibody (HV545014) is a rabbit polyclonal antibody detecting UXT in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human UXT (Glu15-His157). | ||||||||
| Цель | ART-27, Protein UXT, Ubiquitously expressed transcript protein, Androgen receptor trapped clone 27 protein, UXT | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q9UBK9 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Protein UXT is a ~18 kDa protein. Involved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor AR-mediated transcription. Together with URI1, associates with chromatin to the NKX3-1 promoter region. Negatively regulates the transcriptional activity of the estrogen receptor ESR1 by inducing its translocation into the cytoplasm. May act as nuclear chaperone that facilitates the formation of the NF-kappa-B enhanceosome and thus positively regulates NF-kappa-B transcription activity. 1. Mita, P. et al. (2011) Molecular and cellular biology 31, 3639-52. PMID: 21730289 2. Sánchez-Morgan, N. et al. (2017) Journal of cellular biochemistry 118, 2347-2356. PMID: 28106301 3. Markus, SM. et al. (2002) Molecular biology of the cell 13, 670-82. PMID: 11854421 4. Sun, S. et al. (2007) The Journal of cell biology 178, 231-44. PMID: 17620405 5. Huang, Y. et al. (2011) Molecular biology of the cell 22, 1389-97. PMID: 21307340 6. Moss, TN. et al. (2007) In vitro cellular & developmental biology. Animal 43, 139-46. PMID: 17554592 | ||||||||
| Примечание | For research use only. |
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