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| カタログ番号 | VK079014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-VP2 Polyclonal Antibody (VK079014) is a rabbit polyclonal antibody detecting 1B VP2 mature peptide; 1B VP2 mature peptide in ELISA, IHC, WB.
Highlights
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| 種反応性 | Hepatitis A virus (HAV) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant hav VP2 (Asp1-Gln222). | ||||||||
| ターゲット | 1B VP2 mature peptide; 1B VP2 mature peptide | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P08617, Q67825, Q9DWR1, Q02381, P31788, Q05794, P13901, P06442, A5LGW7, P14553, Q5Y944, Q8V0N6, A3FMB2, P06441 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Genome polyprotein (VP2) is a ~251 kDa protein. Capsid proteins VP1, VP2, and VP3 form a closed capsid enclosing the viral positive strand RNA genome. All these proteins contain a beta-sheet structure called beta-barrel jelly roll. Together they form an icosahedral capsid (T=3) composed of 60 copies of each VP1, VP2, and VP3, with a diameter of approximately 300 Angstroms. VP1 is situated at the 12 fivefold axes, whereas VP2 and VP3 are located at the quasi-sixfold axes. The naked capsid interacts with the host receptor HAVCR1 to provide virion attachment to and probably entry into the target cell. 1. Wang, X. et al. (2015) Nature 517, 85-88. PMID: 25327248 2. Wang, X. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, 770-775. PMID: 28074040 3. Silberstein, E. et al. (2001) Journal of virology 75, 717-25. PMID: 11134285 4. Costafreda, MI. et al. (2018) Journal of virology 92. PMID: 29437974 5. Feigelstock, D. et al. (1998) Journal of virology 72, 6621-8. PMID: 9658108 | ||||||||
| 注意事項 | For research use only. |
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