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Anti-VPS26A Polyclonal Antibody (HB599014)

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Vista general
Número de catálogoHB599014
Descripción
Anti-VPS26A Polyclonal Antibody (HB599014) is a rabbit polyclonal antibody detecting Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26A; hVPS26; VPS26A; VPS26 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Frog.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant human VPS26A (Met1-Gln305).
Objetivo Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26A; hVPS26; VPS26A; VPS26
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso O75436, P40336, Q6AY86, Q0VD53, Q6DFU4, Q6IRD0, Q6TNP8
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Vacuolar protein sorting-associated protein 26A (VPS26A) is a ~38 kDa protein. Acts as a component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway.

1. Seaman, MN. (2004) The Journal of cell biology 165, 111-22. PMID: 15078902
2. Arighi, CN. et al. (2004) The Journal of cell biology 165, 123-33. PMID: 15078903
3. Vergés, M. et al. (2004) Nature cell biology 6, 763-9. PMID: 15247922
4. Harbour, ME. et al. (2012) The Biochemical journal 442, 209-20. PMID: 22070227
5. Harbour, ME. et al. (2010) Journal of cell science 123, 3703-17. PMID: 20923837
6. Fjorback, AW. et al. (2012) The Journal of neuroscience : the official journal of the Society for Neuroscience 32, 1467-80. PMID: 22279231
7. Gullapalli, A. et al. (2006) Molecular biology of the cell 17, 1228-38. PMID: 16407403
8. Temkin, P. et al. (2011) Nature cell biology 13, 715-21. PMID: 21602791
Nota For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-VPS26A Polyclonal Antibody

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