Anti-VPS26A Polyclonal Antibody (HB599014)

Name: Anti-VPS26A Polyclonal Antibody
Brand: abinScience
SKU: HB599014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

Nombre :

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SDS

Aperçu

Numéro de catalogue

HB599014

Description

Anti-VPS26A Polyclonal Antibody (HB599014) is a rabbit polyclonal antibody detecting Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26A; hVPS26; VPS26A; VPS26 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Frog.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant human VPS26A (Met1-Gln305).

Cible

Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26A; hVPS26; VPS26A; VPS26

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

O75436, P40336, Q6AY86, Q0VD53, Q6DFU4, Q6IRD0, Q6TNP8

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Vacuolar protein sorting-associated protein 26A (VPS26A) is a ~38 kDa protein. Acts as a component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway.

1. Seaman, MN. (2004) The Journal of cell biology 165, 111-22. PMID: 15078902

2. Arighi, CN. et al. (2004) The Journal of cell biology 165, 123-33. PMID: 15078903

3. Vergés, M. et al. (2004) Nature cell biology 6, 763-9. PMID: 15247922

4. Harbour, ME. et al. (2012) The Biochemical journal 442, 209-20. PMID: 22070227

5. Harbour, ME. et al. (2010) Journal of cell science 123, 3703-17. PMID: 20923837

6. Fjorback, AW. et al. (2012) The Journal of neuroscience : the official journal of the Society for Neuroscience 32, 1467-80. PMID: 22279231

7. Gullapalli, A. et al. (2006) Molecular biology of the cell 17, 1228-38. PMID: 16407403

8. Temkin, P. et al. (2011) Nature cell biology 13, 715-21. PMID: 21602791

Note

For research use only

Images

Reférences

Fiche technique

Anti-VPS26A Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-VPS26A Polyclonal Antibody (HB599014)

Aperçu

Images

Reférences

Fiche technique

SDS