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| カタログ番号 | HB599014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-VPS26A Polyclonal Antibody (HB599014) is a rabbit polyclonal antibody detecting Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26A; hVPS26; VPS26A; VPS26 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Frog.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human VPS26A (Met1-Gln305). | ||||||||
| ターゲット | Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26A; hVPS26; VPS26A; VPS26 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O75436, P40336, Q6AY86, Q0VD53, Q6DFU4, Q6IRD0, Q6TNP8 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Vacuolar protein sorting-associated protein 26A (VPS26A) is a ~38 kDa protein. Acts as a component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway. 1. Seaman, MN. (2004) The Journal of cell biology 165, 111-22. PMID: 15078902 2. Arighi, CN. et al. (2004) The Journal of cell biology 165, 123-33. PMID: 15078903 3. Vergés, M. et al. (2004) Nature cell biology 6, 763-9. PMID: 15247922 4. Harbour, ME. et al. (2012) The Biochemical journal 442, 209-20. PMID: 22070227 5. Harbour, ME. et al. (2010) Journal of cell science 123, 3703-17. PMID: 20923837 6. Fjorback, AW. et al. (2012) The Journal of neuroscience : the official journal of the Society for Neuroscience 32, 1467-80. PMID: 22279231 7. Gullapalli, A. et al. (2006) Molecular biology of the cell 17, 1228-38. PMID: 16407403 8. Temkin, P. et al. (2011) Nature cell biology 13, 715-21. PMID: 21602791 | ||||||||
| 注意事項 | For research use only |
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