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| カタログ番号 | HV550014 | ||||||||
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| 説明 |
Anti-WDFY1 Polyclonal Antibody (HV550014) is a rabbit polyclonal antibody detecting WDFY1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human WDFY1 (Met1-His410). | ||||||||
| ターゲット | FENS-1, Zinc finger FYVE domain-containing protein 17, WD40- and FYVE domain-containing protein 1, FYVE domain-containing protein localized to endosomes 1, KIAA1435, ZFYVE17, WDFY1, FENS1, WD repeat and FYVE domain-containing protein 1, Phosphoinositide-binding protein 1, WDF1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8IWB7 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | WD repeat and FYVE domain-containing protein 1 (WDFY1) is a ~46 kDa protein. Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines. 1. Hu, YH. et al. (2015) EMBO reports 16, 447-55. PMID: 25736436 | ||||||||
| 注意事項 | For research use only. |
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