Anti-WNT5A Polyclonal Antibody (MW294014)

Name: Anti-WNT5A Polyclonal Antibody
Brand: abinScience
SKU: MW294014
Price: 168 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug

Número:

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Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

MW294014

Descripción

Anti-WNT5A Polyclonal Antibody (MW294014) is a rabbit polyclonal antibody detecting WNT5A in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Alopias vulpinus, and Ambystoma mexicanum.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Mouse WNT5A (Ile62-Lys380).

Objetivo

Protein Wnt-5a, WNT5A

Purificación

Purified by antigen affinity column.

Número de acceso

P22725

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Protein Wnt-5a (WNT5A) is a ~42 kDa protein. Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation.

1. Kurayoshi, M. et al. (2007) The Biochemical journal 402, 515-23. PMID: 17117926

2. Mikels, AJ. et al. (2006) PLoS biology 4, e115. PMID: 16602827

3. Yamaguchi, TP. et al. (1999) Development (Cambridge, England) 126, 1211-23. PMID: 10021340

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-WNT5A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo