Please ensure Javascript is enabled for purposes of website accessibility
Contactez-nous Contactez-nous
FR
Accueil > Products > Anticorps > Anticorps Primaires

Anti-XPO4 Polyclonal Antibody (HC006014)

Fiche technique Partager le produit Copier les informations
Prix(USD) : --
Spécification :
  • 50ug
  • 100ug
Nombre :
Contactez-nous

  • Aperçu

  • Images

  • Reférences

  • Fiche technique

  • SDS

Aperçu
Numéro de catalogueHC006014
Description
Anti-XPO4 Polyclonal Antibody (HC006014) is a rabbit polyclonal antibody in ELISA, IHC, WB. Suitable for Human, Chicken, Mouse, Frog, and Zebrafish.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant human XPO4 (Met28-Asn256).
Niveau d'endotoxines Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Numéro d'accès Q9C0E2, Q5ZMR9, Q9ESJ0, Q499Y0, Q802D3
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Exportin-4 (XPO4) is a ~130 kDa protein. Mediates the nuclear export of proteins (cargos), such as EIF5A, SMAD3 and isoform M2 of PKM (PKM2). In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO4 then return to the nuclear compartment and mediate another round of transport.

1. Lipowsky, G. et al. (2000) The EMBO journal 19, 4362-71. PMID: 10944119
2. Kurisaki, A. et al. (2006) Molecular and cellular biology 26, 1318-32. PMID: 16449645
3. Bhardwaj, A. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, E538-47. PMID: 26787900
Note For research use only
Images
Reférences
Fiche technique
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

Contactez-nous pour les devis personnalisés, les demandes en gros et tout autre problème.

Courrier : [email protected]

Liste des distributeurs

Obtenir un devis gratuit
Anti-XPO4 Polyclonal Antibody

Accès rapide

Contactez-nous

  • +86-027-65523339

  • [email protected]

  • Bâtiment C, No. 666, Rue Shendunsi, Wuhan, 430206, Chine

  • linkedin
  • Ins
  • youtube
  • youtube
Droit d'auteur © 2026 abinScience. Tous droits réservés. Tous les produits sont uniquement à usage de recherche