Anti-XPO4 Polyclonal Antibody (HC006014)

Name: Anti-XPO4 Polyclonal Antibody
Brand: abinScience
SKU: HC006014
Price: 168 USD
Availability: InStock

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Обзор

Каталожный номер

HC006014

Описание

Anti-XPO4 Polyclonal Antibody (HC006014) is a rabbit polyclonal antibody in ELISA, IHC, WB. Suitable for Human, Chicken, Mouse, Frog, and Zebrafish.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human XPO4 (Met28-Asn256).

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

Q9C0E2, Q5ZMR9, Q9ESJ0, Q499Y0, Q802D3

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Exportin-4 (XPO4) is a ~130 kDa protein. Mediates the nuclear export of proteins (cargos), such as EIF5A, SMAD3 and isoform M2 of PKM (PKM2). In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO4 then return to the nuclear compartment and mediate another round of transport.

1. Lipowsky, G. et al. (2000) The EMBO journal 19, 4362-71. PMID: 10944119

2. Kurisaki, A. et al. (2006) Molecular and cellular biology 26, 1318-32. PMID: 16449645

3. Bhardwaj, A. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, E538-47. PMID: 26787900

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-XPO4 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-XPO4 Polyclonal Antibody (HC006014)

Обзор

Изображения

Ссылки

Даташит

SDS