

| Numéro de catalogue | JB195014 | ||||||||
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| Description |
Anti-Yeast HYR1/GPX3 Polyclonal Antibody (JB195014) is a rabbit polyclonal antibody detecting GPX3. Suitable for Yeast.
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| Reactivité des espèces | Saccharomyces cerevisiae (Baker's yeast) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Yeast HYR1/GPX3 (Met1-Glu163). | ||||||||
| Cible | EC:1.11.1.24, GPX3, GPx 3, Glutathione peroxidase homolog 3, Glutathione peroxidase-like peroxiredoxin HYR1, HYR1, Hydrogen peroxide resistance protein 1, ORP1, Oxidant receptor peroxidase 1, PHGPx3, Phospholipid hydroperoxide glutathione peroxidase 3 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P40581 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Glutathione peroxidase-like peroxiredoxin HYR1 (GPX3) is a ~18 kDa protein. Involved in oxidative stress response and redox homeostasis. Functions as a sensor and transducer of hydroperoxide stress. In response to hydroperoxide stress it oxidizes (activates) the transcription activator YAP1, which is involved in transcription activation of genes of the oxidative stress response pathway. May also play a direct role in hydroperoxide scavenging, being the most active of three closely related S.cerevisiae peroxiredoxins (GPX1, GPX2, and HYR1/GPX3) with respect to peroxide and lipid hydroperoxide reduction. The three enzymes are not required for the glutaredoxin-mediated antioxidant function. | ||||||||
| Note | For research use only. |
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