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Anti-Yersinia pestis Plasminogen activator/Pla Polyclonal Antibody (JN173024)

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Vista general
Número de catálogoJN173024
Descripción
Anti-Yersinia pestis Plasminogen activator/Pla Polyclonal Antibody (JN173024) is a rabbit polyclonal antibody detecting Plasminogen activator. Suitable for Yersinia pestis.
Reactividad de especiesYersinia pestis
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Yersinia pestis Plasminogen activator/Pla (Ala21-Phe312).
Objetivo Coagulase/fibrinolysin, EC:3.4.23.48, Pla, Plasminogen activator, pla
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso P17811
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Plasminogen activator is a ~34 kDa protein. In the mammalian host activates (cleaves) plasminogen to generate the serine protease plasmin. Plasmin degrades fibrin clots (fibrinolysis) and facilitates bacterial cell migration, enabling rapid dissemination of bacteria from the initial site of infection (Probable). Cleaves host plasminogen to generate plasmin and probably also has autocatalytic activity. Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lower temperatures (28 degrees Celsius). Cleaves plasminogen; plasminogen cleavage is much higher than coagulase activity.

1. Eren, E. et al. (2010) Structure (London, England : 1993) 18, 809-18. PMID: 20637417
2. Eren, E. et al. (2012) The Journal of biological chemistry 287, 23971-6. PMID: 22645135
3. McDonough, KA. et al. (1989) Molecular microbiology 3, 767-75. PMID: 2526282
4. Sodeinde, OA. et al. (1989) Infection and immunity 57, 1517-23. PMID: 2651310
Nota For research use only
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Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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