Anti-Yersinia pestis Plasminogen activator/Pla Polyclonal Antibody (JN173024)

Name: Anti-Yersinia pestis Plasminogen activator/Pla Polyclonal Antibody
Brand: abinScience
SKU: JN173024
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

JN173024

Description

Anti-Yersinia pestis Plasminogen activator/Pla Polyclonal Antibody (JN173024) is a rabbit polyclonal antibody detecting Plasminogen activator. Suitable for Yersinia pestis.

Reactivité des espèces

Yersinia pestis

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Yersinia pestis Plasminogen activator/Pla (Ala21-Phe312).

Cible

Coagulase/fibrinolysin, EC:3.4.23.48, Pla, Plasminogen activator, pla

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

P17811

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

Plasminogen activator is a ~34 kDa protein. In the mammalian host activates (cleaves) plasminogen to generate the serine protease plasmin. Plasmin degrades fibrin clots (fibrinolysis) and facilitates bacterial cell migration, enabling rapid dissemination of bacteria from the initial site of infection (Probable). Cleaves host plasminogen to generate plasmin and probably also has autocatalytic activity. Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lower temperatures (28 degrees Celsius). Cleaves plasminogen; plasminogen cleavage is much higher than coagulase activity.

1. Eren, E. et al. (2010) Structure (London, England : 1993) 18, 809-18. PMID: 20637417

2. Eren, E. et al. (2012) The Journal of biological chemistry 287, 23971-6. PMID: 22645135

3. McDonough, KA. et al. (1989) Molecular microbiology 3, 767-75. PMID: 2526282

4. Sodeinde, OA. et al. (1989) Infection and immunity 57, 1517-23. PMID: 2651310

Note

For research use only

Images

Reférences

Fiche technique

Anti-Yersinia pestis Plasminogen activator/Pla Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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