

| Numéro de catalogue | HC522014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-ZBTB16 Polyclonal Antibody (HC522014) is a rabbit polyclonal antibody detecting Zinc finger and BTB domain-containing protein 16; Promyelocytic leukemia zinc finger protein; Zinc finger protein 145; Zinc finger protein PLZF; ZBTB16; PLZF; ZNF145 in ELISA, IHC, WB. Suitable for Human and Zebrafish.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant human ZBTB16 (Ile402-Val673). | ||||||||
| Cible | Zinc finger and BTB domain-containing protein 16; Promyelocytic leukemia zinc finger protein; Zinc finger protein 145; Zinc finger protein PLZF; ZBTB16; PLZF; ZNF145 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q05516, Q802Y8 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Zinc finger and BTB domain-containing protein 16 (ZBTB16) is a ~74 kDa protein. Acts as a transcriptional repressor. Transcriptional repression may be mediated through recruitment of histone deacetylases to target promoters. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. 1. Melnick, AM. et al. (2000) Molecular and cellular biology 20, 2075-86. PMID: 10688654 2. Lin, DY. et al. (2013) Journal of biomedical science 20, 98. PMID: 24359566 3. Furukawa, M. et al. (2003) Nature cell biology 5, 1001-7. PMID: 14528312 | ||||||||
| Note | For research use only |
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