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| カタログ番号 | HC522014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-ZBTB16 Polyclonal Antibody (HC522014) is a rabbit polyclonal antibody detecting Zinc finger and BTB domain-containing protein 16; Promyelocytic leukemia zinc finger protein; Zinc finger protein 145; Zinc finger protein PLZF; ZBTB16; PLZF; ZNF145 in ELISA, IHC, WB. Suitable for Human and Zebrafish.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human ZBTB16 (Ile402-Val673). | ||||||||
| ターゲット | Zinc finger and BTB domain-containing protein 16; Promyelocytic leukemia zinc finger protein; Zinc finger protein 145; Zinc finger protein PLZF; ZBTB16; PLZF; ZNF145 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q05516, Q802Y8 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Zinc finger and BTB domain-containing protein 16 (ZBTB16) is a ~74 kDa protein. Acts as a transcriptional repressor. Transcriptional repression may be mediated through recruitment of histone deacetylases to target promoters. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. 1. Melnick, AM. et al. (2000) Molecular and cellular biology 20, 2075-86. PMID: 10688654 2. Lin, DY. et al. (2013) Journal of biomedical science 20, 98. PMID: 24359566 3. Furukawa, M. et al. (2003) Nature cell biology 5, 1001-7. PMID: 14528312 | ||||||||
| 注意事項 | For research use only |
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