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Anti-ZEBOV Glycoprotein Recombinant Antibody (mAb100) (VK623023)

Anti-ZEBOV Glycoprotein Recombinant Antibody (mAb100)
Anti-ZEBOV Glycoprotein Recombinant Antibody (mAb100)
Цена(USD):
Спецификация:
  • 20ug
  • 50ug
  • 100ug
  • 1mg
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерVK623023
Реактивность видовZaire ebolavirus (ZEBOV) (Zaire Ebola virus)
ПримененияELISA
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG
ID клонаmAb100
Цель Envelope glycoprotein, GP, GP1, GP1,2, GP1,2-delta, GP2, Shed GP
Уровень эндотоксинов < 10 EU/mg
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа Q05320
RRID Anti-ZEBOV GP/Envelope glycoprotein Antibody (mAb100) (abinScience Cat# VK623023, RRID:AB_3727244)
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

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Информация об использовании продукта
Применение Разбавление
ELISA 1:2000-1:20000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Envelope glycoprotein (GP) is a ~74 kDa protein. Trimeric GP1,2 complexes form the virion surface spikes and mediate the viral entry processes, with GP1 acting as the receptor-binding subunit and GP2 as the membrane fusion subunit. At later times of infection, down-regulates the expression of various host cell surface molecules that are essential for immune surveillance and cell adhesion. Down-modulates several integrins including ITGA1, ITGA2, ITGA3, ITGA4, ITGA5, ITGA6, ITGAV and ITGB1. This decrease in cell adhesion molecules may lead to cell detachment, contributing to the disruption of blood vessel integrity and hemorrhages developed during infection (cytotoxicity). Interacts with host TLR4 and thereby stimulates the differentiation and activation of monocytes leading to bystander death of T-lymphocytes.

Примечание For research use only.
Изображения
  • Anti-ZEBOV Glycoprotein Recombinant Antibody (mAb100)

    SDS-PAGE

    SDS-PAGE for Anti-ZEBOV GP/Envelope glycoprotein Antibody (mAb100)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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