Anti-ZEBOV NP/Nucleoprotein Recombinant Antibody (KZ51) (VK518023)

Name: Anti-ZEBOV NP/Nucleoprotein Recombinant Antibody (KZ51)
Brand: abinScience
SKU: VK518023
Price: 191 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

VK518023

Reactividad de especies

Zaire ebolavirus (ZEBOV) (Zaire Ebola virus)

Aplicaciones

ELISA, IF

Especie huésped

Human

Clonalidad

Monoclonal

Isotipo

IgG

ID de clon

KZ51

Objetivo

NP, Nucleoprotein, Nucleocapsid protein

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P18272

RRID

Anti-ZEBOV NP/Nucleoprotein Antibody (KZ51) (abinScience Cat# VK518023, RRID:AB_3727247)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Nucleoprotein (NP) is a ~83 kDa protein. Oligomerizes into helical capsid to encapsidate the viral genome, protecting it from nucleases and the cellular innate immune response. VP35 binds to and stabilizes monomeric NP, keeping it soluble. Upon virus replication, NP is recruited to bind cooperatively viral genomic RNA and VP35 is released. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. The nucleocapsid is helical with a pitch of 10.81 NP per turn and a diameter of about 22nm.

1. Johnson, RF. et al. (2006) Virology journal 3, 31. PMID: 16719918

2. Leung, DW. et al. (2015) Cell reports 11, 376-89. PMID: 25865894

3. Kirchdoerfer, RN. et al. (2015) Cell reports 12, 140-149. PMID: 26119732

4. Sugita, Y. et al. (2018) Nature 563, 137-140. PMID: 30333622

5. Wan, W. et al. (2017) Nature 551, 394-397. PMID: 29144446

6. Beniac, DR. et al. (2012) PloS one 7, e29608. PMID: 22247782

7. Kirchdoerfer, RN. et al. (2016) PLoS pathogens 12, e1005937. PMID: 27755595

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-ZEBOV NP/Nucleoprotein Antibody (KZ51)

Referencias

Datasheet

Anti-ZEBOV NP/Nucleoprotein Recombinant Antibody (KZ51).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo