Anti-ZEBOV NP/Nucleoprotein Recombinant Antibody (KZ51) (VK518023)

Name: Anti-ZEBOV NP/Nucleoprotein Recombinant Antibody (KZ51)
Brand: abinScience
SKU: VK518023
Price: 191 USD
Availability: InStock

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Spécification :

50ug
100ug
1mg

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

VK518023

Reactivité des espèces

Zaire ebolavirus (ZEBOV) (Zaire Ebola virus)

Applications

ELISA, IF

Espèce hôte

Human

Clonalité

Monoclonal

Isotype

IgG

ID de clone

KZ51

Cible

NP, Nucleoprotein, Nucleocapsid protein

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P18272

RRID

Anti-ZEBOV NP/Nucleoprotein Antibody (KZ51) (abinScience Cat# VK518023, RRID:AB_3727247)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Nucleoprotein (NP) is a ~83 kDa protein. Oligomerizes into helical capsid to encapsidate the viral genome, protecting it from nucleases and the cellular innate immune response. VP35 binds to and stabilizes monomeric NP, keeping it soluble. Upon virus replication, NP is recruited to bind cooperatively viral genomic RNA and VP35 is released. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. The nucleocapsid is helical with a pitch of 10.81 NP per turn and a diameter of about 22nm.

1. Johnson, RF. et al. (2006) Virology journal 3, 31. PMID: 16719918

2. Leung, DW. et al. (2015) Cell reports 11, 376-89. PMID: 25865894

3. Kirchdoerfer, RN. et al. (2015) Cell reports 12, 140-149. PMID: 26119732

4. Sugita, Y. et al. (2018) Nature 563, 137-140. PMID: 30333622

5. Wan, W. et al. (2017) Nature 551, 394-397. PMID: 29144446

6. Beniac, DR. et al. (2012) PloS one 7, e29608. PMID: 22247782

7. Kirchdoerfer, RN. et al. (2016) PLoS pathogens 12, e1005937. PMID: 27755595

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-ZEBOV NP/Nucleoprotein Antibody (KZ51)

Reférences

Fiche technique

Anti-ZEBOV NP/Nucleoprotein Recombinant Antibody (KZ51).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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