

| Каталожный номер | VK518023 | ||||
|---|---|---|---|---|---|
| Реактивность видов | Zaire ebolavirus (ZEBOV) (Zaire Ebola virus) | ||||
| Применения | ELISA, IF | ||||
| Хозяинский вид | Human | ||||
| Клоональность | Monoclonal | ||||
| Изотип | IgG | ||||
| ID клона | KZ51 | ||||
| Цель | NP, Nucleoprotein, Nucleocapsid protein | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | P18272 | ||||
| RRID | Anti-ZEBOV NP/Nucleoprotein Antibody (KZ51) (abinScience Cat# VK518023, RRID:AB_3727247) |
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| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Фон | Nucleoprotein (NP) is a ~83 kDa protein. Oligomerizes into helical capsid to encapsidate the viral genome, protecting it from nucleases and the cellular innate immune response. VP35 binds to and stabilizes monomeric NP, keeping it soluble. Upon virus replication, NP is recruited to bind cooperatively viral genomic RNA and VP35 is released. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. The nucleocapsid is helical with a pitch of 10.81 NP per turn and a diameter of about 22nm. 1. Johnson, RF. et al. (2006) Virology journal 3, 31. PMID: 16719918 2. Leung, DW. et al. (2015) Cell reports 11, 376-89. PMID: 25865894 3. Kirchdoerfer, RN. et al. (2015) Cell reports 12, 140-149. PMID: 26119732 4. Sugita, Y. et al. (2018) Nature 563, 137-140. PMID: 30333622 5. Wan, W. et al. (2017) Nature 551, 394-397. PMID: 29144446 6. Beniac, DR. et al. (2012) PloS one 7, e29608. PMID: 22247782 7. Kirchdoerfer, RN. et al. (2016) PLoS pathogens 12, e1005937. PMID: 27755595 | ||||
| Примечание | For research use only. |

SDS-PAGE for Anti-ZEBOV NP/Nucleoprotein Antibody (KZ51)
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