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| カタログ番号 | VK095014 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-ZEBOV VP24 Polyclonal Antibody (VK095014) is a rabbit polyclonal antibody detecting VP24 in ELISA, IHC, WB. Suitable for Zaire ebolavirus.
Highlights
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| 種反応性 | Zaire ebolavirus (ZEBOV) (Zaire Ebola virus) | ||||
| アプリケーション | ELISA, IHC, WB | ||||
| 宿主種 | Rabbit | ||||
| クローン性 | Polyclonal | ||||
| アイソタイプ | IgG | ||||
| 免疫原 | E. coli - derived recombinant ZEBOV VP24 (Met1-Ile251). | ||||
| ターゲット | Membrane-associated protein VP24, Ebola VP24, eVP24, VP24 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 精製 | Purified by antigen affinity column. | ||||
| アクセッション番号 | Q6V1Q3, Q05322, O11459 | ||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Membrane-associated protein VP24 is a ~28 kDa protein. Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways. Blocks the IFN-induced nuclear accumulation of host phosphorylated STAT1 by interacting with the STAT1-binding region of host importins. Alternatively also interacts directly with host STAT1 and may additionally inhibit its non-phosphorylated form. Plays a role in assembly of viral nucleocapsid and virion budding. May act as a minor matrix protein that plays a role in assembly of viral nucleocapsid and virion budding. | ||||
| 注意事項 | For research use only |
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