

| Каталожный номер | VK661014 | ||||
|---|---|---|---|---|---|
| Описание |
Anti-ZEBOV VP35 Polyclonal Antibody (VK661014) is a rabbit polyclonal antibody detecting VP35 in ELISA, IHC, WB. Suitable for Reston ebolavirus, Zaire ebolavirus, and Sudan ebolavirus.
Highlights
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| Реактивность видов | Zaire ebolavirus (ZEBOV) (Zaire Ebola virus) | ||||
| Применения | ELISA, IHC, WB | ||||
| Хозяинский вид | Rabbit | ||||
| Клоональность | Polyclonal | ||||
| Изотип | IgG | ||||
| Иммуноген | E. coli - derived recombinant ZEBOV VP35 (Gly215-Ile340). | ||||
| Цель | Polymerase cofactor VP35, Ebola VP35, eVP35, VP35 | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Очистка | Purified by antigen affinity column. | ||||
| Номер доступа | Q8JPY0, Q5XX07, Q05127, Q6V1Q9, Q91DE0 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Фон | Polymerase cofactor VP35 is a ~36 kDa protein. Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling. Acts as a polymerase cofactor in the RNA polymerase transcription and replication complexes. Serves as nucleoprotein/NP monomer chaperone prior to the formation of the large oligomeric RNA-bound complexes. Part of the external layer of the nucleocapsid, likely tethering the nucleocapsid to the matrix and membrane. Regulates RNA synthesis by modulating NP-RNA interactions and interacting with DYNLL1. 1. Kimberlin, CR. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 314-9. PMID: 20018665 | ||||
| Примечание | For research use only |
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