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| カタログ番号 | VK783014 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-ZEBOV VP40 Polyclonal Antibody (VK783014) is a rabbit polyclonal antibody detecting VP40 in ELISA, IHC, WB. Suitable for Zaire ebolavirus.
Highlights
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| 種反応性 | Zaire ebolavirus (ZEBOV) (Zaire Ebola virus) | ||||
| アプリケーション | ELISA, IHC, WB | ||||
| 宿主種 | Rabbit | ||||
| クローン性 | Polyclonal | ||||
| アイソタイプ | IgG | ||||
| 免疫原 | E. coli - derived recombinant ZEBOV VP40 (Asn31-Lys326). | ||||
| ターゲット | Matrix protein VP40, Ebola VP40, eVP40, Membrane-associated protein VP40, VP40 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 精製 | Purified by antigen affinity column. | ||||
| アクセッション番号 | Q77DJ6, Q05128, Q2PDK5 | ||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Matrix protein VP40 is a ~35 kDa protein. Plays an essential role virus particle assembly and budding. Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD6IP/ALIX, NEDD4 or TGS101. The interaction with host E3 ubiquitin ligase SMURF2 also facilitates virus budding. May play a role in immune cell dysfunction by being packaged into exosomes that can decrease the viability of recipient cells (via RNAi suppression and exosome-bystander apoptosis). | ||||
| 注意事項 | For research use only |
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