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| カタログ番号 | VK656014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-ZIKV NS1 Polyclonal Antibody (VK656014) is a rabbit polyclonal antibody detecting NS1. Suitable for Zika virus.
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| 種反応性 | Zika virus (ZIKV) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant ZIKV NS1 (Val796-Gly1158). | ||||||||
| ターゲット | Capsid protein, Capsid protein C, Core protein, EC:2.1.1.56, EC:2.1.1.57, EC:2.7.7.48, EC:3.4.21.91, EC:3.6.1.15, EC:3.6.4.13, Envelope protein E, Flavivirin protease NS2B regulatory subunit, Flavivirin protease NS3 catalytic subunit, Genome polyprotein, Matrix protein, NS1, NS2A, NS4A, NS4B, NS5, Non-structural protein 1, Non-structural protein 2A, Non-structural protein 2B, Non-structural protein 3, Non-structural protein 4A, Non-structural protein 4B, Peptide 2k, Peptide pr, Peptide precursor, Precursor membrane protein, Protein prM, RNA-directed RNA polymerase/Methyltransferase NS5, Serine protease NS3, Serine protease subunit NS2B, Small envelope protein M | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | A0A024B7W1 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Initiator protein NS1 is a ~74 kDa protein. Multifunctional protein essential for viral DNA replication, which cooperatively interacts with the viral DNA origin of replication and transactivates several promoters including the viral p6 promoter. Binds the origin of replication and performs an endonucleolytic nick within a conserved sequence in the viral genome, thereby initiating the rolling circle replication (RCR). Participates in the transcriptional regulation the viral p6 promoter that regulates all viral transcripts and the cellular CDN1A or IL6 promoters. Transactivates several host promoters some of which induce the S cell cycle phase for the production of host replicative proteins. Up-regulates the expression of host E2F4 and E2F5 and interacts with both these factors thereby inhibiting the host cell cycle G2/M transition. | ||||||||
| 注意事項 | For research use only |
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