HEK293T Human CD46 Stable Cell Line (HB735818)

Vista general

Número de catálogo	HB735818
Descripción	HEK293T Mouse CD46 Stable Cell Line (HB735818) is a stable cell line expressing CD46. Engineered for consistent, high-level target expression in research applications. Highlights ●Stable Expression — Engineered for consistent, high-level target expression.
Número de acceso	P15529
Aplicaciones	FCM
Especie huésped	HEK293T
Especies	Mouse
Objetivo	CD46
Método de detección	Colorimetric
Tipo de muestra	Plasma, Serum
Tipo de ensayo	Quantitative
Rango	1.56 - 100 ng/mL
Sensibilidad	0.25 ng/mL
Recuperación	80-120%
Propiedades	Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL)
Envío	2-8 ℃
Estabilidad y almacenamiento	Frozen in liquid nitrogen.
Especificaciones	1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium
Fondo	Membrane cofactor protein (CD46) is a ~43 kDa protein. Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.
Nota	For research use only

Imágenes

Flow cytometry

Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD46 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

Referencias

Datasheet