

| Каталожный номер | HA529013 |
|---|---|
| Реактивность видов | Human |
| Хозяинский вид | Human |
| Клоональность | Monoclonal |
| Изотип | IgM |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | P0DOX6 |
| RRID | Human IgM Antibody (abinScience Cat# HA529013, RRID:AB_3730102) |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | IgM, Immunoglobulin mu |
| Фон | Immunoglobulin mu heavy chain is a ~63 kDa protein. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. 1. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268 2. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414 3. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170 4. Geisberger, R. et al. (2006) Immunology 118, 429-37. PMID: 16895553 |
| Примечание | For research use only. |
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