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InVivo Plus Anti-Mouse CTLA-4 Antibody(9D9) (MB651209)

InVivo Plus Anti-Mouse CTLA-4 Antibody(9D9)
InVivo Plus Anti-Mouse CTLA-4 Antibody(9D9)
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Vista general
Número de catálogoMB651209
Descripción
InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9) [9D9] (MB651209) is a mouse monoclonal antibody detecting CD152 in in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion. Suitable for Mouse.
Highlights
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesMouse
Aplicacionesin vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2b, kappa
ID de clon9D9
Objetivo CD152, CTLA-4, CTLA4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
Nivel de endotoxinas < 1 EU/mg
Pureza >95% as determined by SDS-PAGE.
Productos asociados pH 7.4 Dilution Buffer
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P09793
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).

Nota For research use only.
Isotype Control Mouse IgG2b, kappa Recombinant Isotype Control Antibody (MPC-11) (MF974207)
Imágenes
  • InVivo Plus Anti-Mouse CTLA-4 Antibody(9D9)

    SDS-PAGE

    SDS-PAGE for InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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