

| Numéro de catalogue | MB651209 |
|---|---|
| Description |
InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9) [9D9] (MB651209) is a mouse monoclonal antibody detecting CD152 in in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion. Suitable for Mouse.
Highlights
|
| Reactivité des espèces | Mouse |
| Applications | in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion |
| Espèce hôte | Mouse |
| Clonalité | Monoclonal |
| Isotype | IgG2b, kappa |
| ID de clone | 9D9 |
| Cible | CD152, CTLA-4, CTLA4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4 |
| Niveau d'endotoxines | < 1 EU/mg |
| Pureté | >95% as determined by SDS-PAGE. |
| Produits associés | pH 7.4 Dilution Buffer |
| Purification | Protein A/G purified from cell culture supernatant. |
| Numéro d'accès | P09793 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Contexte | Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy). |
| Note | For research use only. |
| Isotype Control | Mouse IgG2b, kappa Recombinant Isotype Control Antibody (MPC-11) (MF974207) |

SDS-PAGE for InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9)




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