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InVivo Plus Anti-Mouse CTLA-4 Antibody(9D9) (MB651209)

InVivo Plus Anti-Mouse CTLA-4 Antibody(9D9)
InVivo Plus Anti-Mouse CTLA-4 Antibody(9D9)
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Aperçu
Numéro de catalogueMB651209
Description
InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9) [9D9] (MB651209) is a mouse monoclonal antibody detecting CD152 in in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion. Suitable for Mouse.
Highlights
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesMouse
Applicationsin vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2b, kappa
ID de clone9D9
Cible CD152, CTLA-4, CTLA4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
Niveau d'endotoxines < 1 EU/mg
Pureté >95% as determined by SDS-PAGE.
Produits associés pH 7.4 Dilution Buffer
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P09793
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).

Note For research use only.
Isotype Control Mouse IgG2b, kappa Recombinant Isotype Control Antibody (MPC-11) (MF974207)
Images
  • InVivo Plus Anti-Mouse CTLA-4 Antibody(9D9)

    SDS-PAGE

    SDS-PAGE for InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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