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InVivo Plus Anti-Mouse CTLA-4 Antibody(9D9) (MB651209)

InVivo Plus Anti-Mouse CTLA-4 Antibody(9D9)
InVivo Plus Anti-Mouse CTLA-4 Antibody(9D9)
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概要
カタログ番号MB651209
説明
InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9) [9D9] (MB651209) is a mouse monoclonal antibody detecting CD152 in in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion. Suitable for Mouse.
Highlights
  • ●Multi-Application — Validated across multiple applications.
種反応性Mouse
アプリケーションin vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion
宿主種Mouse
クローン性Monoclonal
アイソタイプIgG2b, kappa
クローンID9D9
ターゲット CD152, CTLA-4, CTLA4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
エンドトキシンレベル < 1 EU/mg
純度 >95% as determined by SDS-PAGE.
関連製品 pH 7.4 Dilution Buffer
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P09793
形態 Liquid
保存バッファー 0.01M PBS pH 7.4.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).

注意事項 For research use only.
Isotype Control Mouse IgG2b, kappa Recombinant Isotype Control Antibody (MPC-11) (MF974207)
イメージ
  • InVivo Plus Anti-Mouse CTLA-4 Antibody(9D9)

    SDS-PAGE

    SDS-PAGE for InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9)

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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