

| Каталожный номер | MB651209 |
|---|---|
| Описание |
InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9) [9D9] (MB651209) is a mouse monoclonal antibody detecting CD152 in in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion. Suitable for Mouse.
Highlights
|
| Реактивность видов | Mouse |
| Применения | in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion |
| Хозяинский вид | Mouse |
| Клоональность | Monoclonal |
| Изотип | IgG2b, kappa |
| ID клона | 9D9 |
| Цель | CD152, CTLA-4, CTLA4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4 |
| Уровень эндотоксинов | < 1 EU/mg |
| Чистота | >95% as determined by SDS-PAGE. |
| Связанные продукты | pH 7.4 Dilution Buffer |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | P09793 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Фон | Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy). |
| Примечание | For research use only. |
| Isotype Control | Mouse IgG2b, kappa Recombinant Isotype Control Antibody (MPC-11) (MF974207) |

SDS-PAGE for InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9)




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