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InVivo Plus Mouse CD8 alpha Antibody(2.43) (MF815109)

InVivo Plus Mouse CD8 alpha Antibody(2.43)
InVivo Plus Mouse CD8 alpha Antibody(2.43)
InVivo Plus Mouse CD8 alpha Antibody(2.43)
InVivo Plus Mouse CD8 alpha Antibody(2.43)
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Vista general
Número de catálogoMF815109
Descripción
InVivo Plus Anti-Mouse CD8a/Lyt2 Antibody (2.43) [2.43] (MF815109) is a rat monoclonal antibody detecting T-cell surface glycoprotein CD8 alpha chain in FCM, in vivo CD8+ T cell depletion, Western blot, Neutralization. Suitable for Mouse.
Highlights
  • ●Multi-Application — Validated across multiple applications.
  • ●Flow Cytometry — Validated for flow cytometry applications.
Reactividad de especiesMouse
AplicacionesFCM, in vivo CD8+ T cell depletion, Western blot, Neutralization
Especie huéspedRat
ClonalidadMonoclonal
IsotipolgG2b
ID de clon2.43
Objetivo CD8a, Cd8a, Lyt-2, Lyt2, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2
Nivel de endotoxinas < 1 EU/mg
Pureza >95% as determined by SDS-PAGE.
Productos asociados pH 7.4 Dilution Buffer
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P01731
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

T-cell surface glycoprotein CD8 alpha chain (CD8a/Lyt2) is a ~27 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.

Nota For research use only.
Isotype Control Rat IgG2b Recombinant Isotype Control Antibody (LTF-2) (RF974107)
Imágenes
  • InVivo Plus Mouse CD8 alpha Antibody(2.43)

    SDS-PAGE

    SDS-PAGE for InVivo Plus Anti-Mouse CD8a/Lyt2 Antibody (2.43)

  • InVivo Plus Mouse CD8 alpha Antibody(2.43)

    Bioactivity

    Detects CD8a/Lyt2 (Catalog No. MF815011) in indirect ELISAs.

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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