



| Numéro de catalogue | MF815109 |
|---|---|
| Description |
InVivo Plus Anti-Mouse CD8a/Lyt2 Antibody (2.43) [2.43] (MF815109) is a rat monoclonal antibody detecting T-cell surface glycoprotein CD8 alpha chain in FCM, in vivo CD8+ T cell depletion, Western blot, Neutralization. Suitable for Mouse.
Highlights
|
| Reactivité des espèces | Mouse |
| Applications | FCM, in vivo CD8+ T cell depletion, Western blot, Neutralization |
| Espèce hôte | Rat |
| Clonalité | Monoclonal |
| Isotype | lgG2b |
| ID de clone | 2.43 |
| Cible | CD8a, Cd8a, Lyt-2, Lyt2, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2 |
| Niveau d'endotoxines | < 1 EU/mg |
| Pureté | >95% as determined by SDS-PAGE. |
| Produits associés | pH 7.4 Dilution Buffer |
| Purification | Protein A/G purified from cell culture supernatant. |
| Numéro d'accès | P01731 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Contexte | T-cell surface glycoprotein CD8 alpha chain (CD8a/Lyt2) is a ~27 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |
| Note | For research use only. |
| Isotype Control | Rat IgG2b Recombinant Isotype Control Antibody (LTF-2) (RF974107) |

SDS-PAGE for InVivo Plus Anti-Mouse CD8a/Lyt2 Antibody (2.43)

Detects CD8a/Lyt2 (Catalog No. MF815011) in indirect ELISAs.




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