InVivo Plus Mouse CD8 alpha Antibody(2.43) (MF815109)

Name: InVivo Plus Mouse CD8 alpha Antibody(2.43)
Brand: abinScience
SKU: MF815109
Price: 128 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	MF815109
説明	InVivo Plus Anti-Mouse CD8a/Lyt2 Antibody (2.43) [2.43] (MF815109) is a rat monoclonal antibody detecting T-cell surface glycoprotein CD8 alpha chain in FCM, in vivo CD8+ T cell depletion, Western blot, Neutralization. Suitable for Mouse. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
種反応性	Mouse
アプリケーション	FCM, in vivo CD8+ T cell depletion, Western blot, Neutralization
宿主種	Rat
クローン性	Monoclonal
アイソタイプ	lgG2b
クローンID	2.43
ターゲット	CD8a, Cd8a, Lyt-2, Lyt2, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2
エンドトキシンレベル	< 1 EU/mg
純度	>95% as determined by SDS-PAGE.
関連製品	pH 7.4 Dilution Buffer
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P01731
形態	Liquid
保存バッファー	0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	T-cell surface glycoprotein CD8 alpha chain (CD8a/Lyt2) is a ~27 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
注意事項	For research use only.
Isotype Control	Rat IgG2b Recombinant Isotype Control Antibody (LTF-2) (RF974107)