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InVivo Plus Mouse CD8 alpha Antibody(2.43)
InVivo Plus Mouse CD8 alpha Antibody(2.43)
InVivo Plus Mouse CD8 alpha Antibody(2.43)
InVivo Plus Mouse CD8 alpha Antibody(2.43)
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Обзор
Каталожный номерMF815109
Описание
InVivo Plus Anti-Mouse CD8a/Lyt2 Antibody (2.43) [2.43] (MF815109) is a rat monoclonal antibody detecting T-cell surface glycoprotein CD8 alpha chain in FCM, in vivo CD8+ T cell depletion, Western blot, Neutralization. Suitable for Mouse.
Highlights
  • ●Multi-Application — Validated across multiple applications.
  • ●Flow Cytometry — Validated for flow cytometry applications.
Реактивность видовMouse
ПримененияFCM, in vivo CD8+ T cell depletion, Western blot, Neutralization
Хозяинский видRat
КлоональностьMonoclonal
ИзотипlgG2b
ID клона2.43
Цель CD8a, Cd8a, Lyt-2, Lyt2, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2
Уровень эндотоксинов < 1 EU/mg
Чистота >95% as determined by SDS-PAGE.
Связанные продукты pH 7.4 Dilution Buffer
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P01731
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

T-cell surface glycoprotein CD8 alpha chain (CD8a/Lyt2) is a ~27 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.

Примечание For research use only.
Isotype Control Rat IgG2b Recombinant Isotype Control Antibody (LTF-2) (RF974107)
Изображения
  • InVivo Plus Mouse CD8 alpha Antibody(2.43)

    SDS-PAGE

    SDS-PAGE for InVivo Plus Anti-Mouse CD8a/Lyt2 Antibody (2.43)

  • InVivo Plus Mouse CD8 alpha Antibody(2.43)

    Bioactivity

    Detects CD8a/Lyt2 (Catalog No. MF815011) in indirect ELISAs.

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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