InVivoMAb Anti-CHIKV Spike Glycoprotein E2 Antibody (m242) (VK425010)

Name: InVivoMAb Anti-CHIKV Spike Glycoprotein E2 Antibody (m242)
Brand: abinScience
SKU: VK425010
Price: 370 USD
Availability: InStock

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100ug
1mg

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Aperçu

Numéro de catalogue	VK425010
Description	InVivoMAb Anti-Chikungunya Virus/CHIKV VLP Antibody (m242) [m242] (VK425010) is a human monoclonal antibody detecting Structural polyprotein in ELISA, Neutralization. Suitable for Chikungunya virus.
Reactivité des espèces	Chikungunya virus (CHIKV)
Applications	ELISA, Neutralization
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1
ID de clone	m242
Cible	Structural polyprotein, p130, Capsid protein, 3.4.21.90, Coat protein, C, Precursor of protein E3/E2, p62, pE2, Assembly protein E3, Spike glycoprotein E2, E2 envelope glycoprotein, 6K protein, Spike glycoprotein E1, E1 envelope glycoprotein
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Produits associés	pH 7.4 Dilution Buffer
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q8JUX5, Q1H8W5, Q5XXP3
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Structural polyprotein (VLP) is a ~138 kDa protein. Forms an icosahedral capsid with a T=4 symmetry composed of 240 copies of the capsid protein surrounded by a lipid membrane through which penetrate 80 spikes composed of trimers of E1-E2 heterodimers. The capsid protein binds to the viral RNA genome at a site adjacent to a ribosome binding site for viral genome translation following genome release. Possesses a protease activity that results in its autocatalytic cleavage from the nascent structural protein. Following its self-cleavage, the capsid protein transiently associates with ribosomes, and within several minutes the protein binds to viral RNA and rapidly assembles into icosahedric core particles. The resulting nucleocapsid eventually associates with the cytoplasmic domain of the spike glycoprotein E2 at the cell membrane, leading to budding and formation of mature virions. 1. Webb, LG. et al. (2020) PLoS pathogens 16, e1008999. PMID: 33057424
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for InVivoMAb Anti-Chikungunya Virus/CHIKV VLP Antibody (m242)

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InVivoMAb Anti-CHIKV Spike Glycoprotein E2 Antibody (m242).pdf

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