InVivoMAb Anti-CHIKV Spike Glycoprotein E2 Antibody (m242) (VK425010)

Name: InVivoMAb Anti-CHIKV Spike Glycoprotein E2 Antibody (m242)
Brand: abinScience
SKU: VK425010
Price: 370 USD
Availability: InStock

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Спецификация:

100ug
1mg

Количество:

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Каталожный номер	VK425010
Описание	InVivoMAb Anti-Chikungunya Virus/CHIKV VLP Antibody (m242) [m242] (VK425010) is a human monoclonal antibody detecting Structural polyprotein in ELISA, Neutralization. Suitable for Chikungunya virus.
Реактивность видов	Chikungunya virus (CHIKV)
Применения	ELISA, Neutralization
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1
ID клона	m242
Цель	Structural polyprotein, p130, Capsid protein, 3.4.21.90, Coat protein, C, Precursor of protein E3/E2, p62, pE2, Assembly protein E3, Spike glycoprotein E2, E2 envelope glycoprotein, 6K protein, Spike glycoprotein E1, E1 envelope glycoprotein
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>95% as determined by SDS-PAGE.
Связанные продукты	pH 7.4 Dilution Buffer
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q8JUX5, Q1H8W5, Q5XXP3
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Structural polyprotein (VLP) is a ~138 kDa protein. Forms an icosahedral capsid with a T=4 symmetry composed of 240 copies of the capsid protein surrounded by a lipid membrane through which penetrate 80 spikes composed of trimers of E1-E2 heterodimers. The capsid protein binds to the viral RNA genome at a site adjacent to a ribosome binding site for viral genome translation following genome release. Possesses a protease activity that results in its autocatalytic cleavage from the nascent structural protein. Following its self-cleavage, the capsid protein transiently associates with ribosomes, and within several minutes the protein binds to viral RNA and rapidly assembles into icosahedric core particles. The resulting nucleocapsid eventually associates with the cytoplasmic domain of the spike glycoprotein E2 at the cell membrane, leading to budding and formation of mature virions. 1. Webb, LG. et al. (2020) PLoS pathogens 16, e1008999. PMID: 33057424
Примечание	For research use only. Not suitable for clinical or therapeutic use.

Изображения

SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Chikungunya Virus/CHIKV VLP Antibody (m242)

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InVivoMAb Anti-CHIKV Spike Glycoprotein E2 Antibody (m242).pdf

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